Paracetamol, Diphenhydramine

Nyquil Hot Remedy

650 MG / SACHET + 25 MG / SACHET Powder For SolutionCanadaMarketedAuthorised 13 Jul 2026

Open in the registerAsk Osler about it

In other countries

The same active substances on other registers, the same brand first.

Antidol Noche 500 MG/25 MG Comprimidos Recubiertos con PeliculaSpain · 500 mg + 25 mg · comprimido recubierto con película · Laboratorios Cinfa S.A.Same substance
Dolomidina 500/25MG Comprimidos Recubiertos con PeliculaSpain · 500 mg + 25 mg · comprimido recubierto con película · Esteve Pharmaceuticals S.A.Same substance
Adol PM 325MG-25MG CapletSaudi Arabia · Gulf Pharmaceutical Industries (Julphar)Same substance
Panadol Night CapletSaudi Arabia · Glaxosmithkline Dungarvan LimitedSame substance

Documents

The official texts, at the regulator.

Two medicines in one question?

Name two or more medicines and Osler runs an interaction check. A severe interaction is stated at the very top of the answer.

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Paracetamol, Diphenhydramine

Nyquil Hot Remedy

650 MG / SACHET + 25 MG / SACHET Powder For SolutionCanadaMarketedAuthorised 13 Jul 2026

Open in the registerAsk Osler about it

In other countries

The same active substances on other registers, the same brand first.

Documents

The official texts, at the regulator.

Two medicines in one question?

Name two or more medicines and Osler runs an interaction check. A severe interaction is stated at the very top of the answer.

Discover Osler

Register entry

Health Canada

Sources and licences

Compiled by Prognia from the public register below; the register’s text is the official one.

Health Canada, Canada

Health Canada, Drug Product Database, drugproduct API, entire response observed 2026-10-10T15:12:07.336870+00:00; native facts projected by Prognia.

Licence: Open Government Licence Canada · Added 13 Oct 2026

Report an error or request removalCorrections from the holder or the register are welcome.

Prognia shows this product information for reference and learning. It is not treatment advice and can lag behind the official text. Always check the current product information and local protocols before prescribing.

At a glance

Active substances: Paracetamol, Diphenhydramine
Strength: 650 MG / SACHET + 25 MG / SACHET
Dosage form: Powder For Solution
Route: Oral
Register: Canada (Health Canada)
Status: Marketed
Authorised: 13 Jul 2026
Registration: DIN 02554380
Marketing authorisation holder: Procter & Gamble INC
ATC code: N02BE01
Group: Nervous system
Supply: NON-PRESCRIPTION DRUGS

Neocitran Extra Strength Cold & Cough NightParacetamol + Diphenhydramine · 650 MG / SACHET + 25 MG / SACHET · Powder For SolutionCanada

Contac ColdParacetamol + Diphenhydramine · 500 MG + 25 MG · TabletCanadaCancelled

Coricidin II Night Time Cold and FluParacetamol + Diphenhydramine · 325 MG + 25 MG · TabletCanadaCancelled

Extra Strength Nighttime Pain Reliever / Sleep AidParacetamol + Diphenhydramine · 500 MG + 25 MG · TabletCanadaCancelled

Extra Strength Tylenol Allergy and CoughParacetamol + Diphenhydramine · 500 MG + 25 MG · TabletCanadaCancelled

Extra Strength Tylenol Pain and Head Cold NightParacetamol + Diphenhydramine · 500 MG + 25 MG · TabletCanadaCancelled

Extra Strength Tylenol Pain and Head Cold Night Rapid ReleaseParacetamol + Diphenhydramine · 500 MG + 25 MG · TabletCanadaCancelled