Marketing-authorisation holder
Holostem s.r.l.
3 medicines in 3 countries, as authorisation holder and manufacturer.
Medicines
Every medicine in the registers under its name, current ones first.
3 medicines
| Medicine | Substance | Country | Status | Authorised |
|---|---|---|---|---|
| Holoclar | Ex vivo expanded autologous human corneal epithelial cells containing stem cells | EU (EMA) | Authorised | 2015 |
| HOLOCLARTessuto vivente da coltura di cellule | Cellule epiteliali corneali umane autologhe espanse ex vivo e contenenti cellule staminali | Italy | Authorised | |
| Holoclar, levend weefsel equivalentLevend weefsel equivalent | Ex-vivo geëxpandeerd autoloog humaan corneaal epitheel dat stamcellen bevat, suspensie van keratinocyten | Netherlands | Authorised | 2015 |
Countries
Where it holds or makes medicines, with how many are current.
| Country | Medicines | Current | Past | Companies |
|---|---|---|---|---|
| European Union (EMA) | 1 | 1 | 0 | CompaniesAll medicines |
| Italy | 1 | 1 | 0 | CompaniesAll medicines |
| Netherlands | 1 | 1 | 0 | CompaniesAll medicines |
Also in the registers of United Kingdom
Therapeutic areas
The ATC groups most of its medicines belong to, largest first.
- OphthalmologicalsSensory organs · ATC S01X
Top substances
The active substances in most of its medicines.
- Ex-vivo geëxpandeerd autoloog humaan corneaal epitheel dat stamcellen bevat, suspensie van keratinocyten1 medicine
- Cellule epiteliali corneali umane autologhe espanse ex vivo e contenenti cellule staminali1 medicine
- Ex vivo expanded autologous human corneal epithelial cells containing stem cells1 medicine
Names in the registers
How the registers spell it, normalised: legal forms, accents and capitals removed.
- holostem
- holostem s r l
- holostem srl
Sources and licences
Compiled by Prognia from the public medicine and company registers below. Logos are not used.
Source: European Medicines Agency (EPAR data).
Licence: EMA reuse policy (source acknowledgement required)
Medicines and Healthcare products Regulatory Agency (MHRA), GOV.UK; Category 1 list; publication updated 25 August 2026; acquired 2026-10-15T08:18:47.757811+00:00; original workbook cells and factual authorization/holder projections adapted under Open Government Licence v3.0.
Licence: Open Government Licence v3.0; exact Crown copyright 2026 publication grant
Agenzia Italiana del Farmaco (AIFA); https://www.aifa.gov.it/documents/20142/3815901/Classe_H_per_principio_attivo_31-05-2026.csv; HTTP Last-Modified Mon, 28 Sep 2026 08:46:40 GMT; acquired 2026-10-13T17:21:06.034935+00:00; native fields retained, source identifier and role projections are adaptations.
Licence: CC BY 4.0; AIFA published open-data catalog
Agenzia Italiana del Farmaco (AIFA); https://www.aifa.gov.it/documents/20142/847386/officine_autorizzate_medicinali_30.06.2026.csv; HTTP Last-Modified Wed, 01 Jul 2026 09:37:30 GMT; acquired 2026-10-13T17:21:05.166252+00:00; native fields retained, source identifier and role projections are adaptations.
Licence: CC BY 4.0; AIFA published open-data catalog
Agenzia Italiana del Farmaco (AIFA); https://drive.aifa.gov.it/farmaci/confezioni_fornitura.csv; HTTP Last-Modified Mon, 12 Oct 2026 23:02:44 GMT; acquired 2026-10-13T17:21:16.224007+00:00; native fields retained, source identifier and role projections are adaptations.
At a glance
- Type
- Marketing-authorisation holder
- Medicines
- 3
- Countries
- 3
- Roles
- Authorisation holder and manufacturer