Group structure
12 companies in 6 countries
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12 companies in 6 countries
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Groups are put together by Prognia from the names regulators publish and from company links; they are not an official corporate structure.
Every medicine of every company in the group, current ones first.
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| Medicine | Substance | Country | Status | Authorised |
|---|---|---|---|---|
| 3% POLOCAINE DENTAL30 mg / ml ยท Liquid | Mepivacaine | Canada | Marketed | 2009 |
| 4% ASTRACAINE DENTAL WITH EPINEPHRINE 1:200,000 (0.005MG/ML)40 mg / ml + 0.005 mg / ml ยท Solution | Articaine, Epinephrine | Canada | Marketed | 2004 |
| 4% ASTRACAINE DENTAL WITH EPINEPHRINE FORTE 1:100,000 (0.01MG/ML)40 mg / ml + 0.01 mg / ml ยท Solution | Articaine, Epinephrine | Canada | Marketed | 2004 |
| 4% CITANEST FORTE DENTAL WITH EPINEPHRINE 1:200,0000.005 mg / ml + 40 mg / ml ยท Solution | Epinephrine, Prilocaine | Canada | Marketed | 2011 |
| 4% CITANEST PLAIN DENTAL40 mg / ml ยท Solution | Prilocaine | Canada | Marketed | 2015 |
| Citanest 3% - Octapressine DENTAL, injectievloeistof voor perineurale toediening 30 mg/ml + 0,54 microgram/mlOplossing voor injectie | Felypressin, Prilocaine | Netherlands | Authorised | 1984 |
| CITANEST FORTE DENTAL0.005mg/ml; 4% ยท Injectable | Epinephrine, Prilocaine | United States | Marketed | 1965 |
| CITANEST PLAIN DENTAL4% ยท Injectable | Prilocaine | United States | Not marketed | 1965 |
| ORAQIX2.5 % + 2.5 % ยท Gel | Lidocaine, Prilocaine | Canada | Marketed | 2010 |
| ORAQIX2.5%; 2.5% ยท GEL | Lidocaine, Prilocaine | United States | Marketed | 2003 |
| ORAQIXGel | Lidocaine, Procaine | Italy | Authorised | |
| ORAQIX GEL PERIODONTAL25 mg + 25 mg ยท Gel periodontal | Lidocaine, Prilocaine | Spain | Marketed | 2005 |
| Oraqix, gel voor peri-odontaal gebruik 25 mg/g + 25 mg/gGel voor peri-odontaal gebruik | Lidocaine, Prilocaine | Netherlands | Authorised | 2005 |
| POLOCAINE W/ LEVONORDEFRIN0.05mg/ml; 2% ยท Injectable | Levonordefrin, Mepivacaine | United States | Not marketed | 1988 |
| Xylocaine 2% - Adrenaline 1:80.000 DENTAL, oplossing voor injectieOplossing voor injectie | Epinephrine, Lidocaine | Netherlands | Authorised | 1986 |
| XYLOCAINE DENTAL2% ยท Injectable | Lidocaine | United States | Not marketed | 1948 |
| XYLOCAINE DENTAL LIDOCAINE HCL 2% AND EPINEPHRINE 1:100,0000.01 mg / ml + 20 mg / ml ยท Solution | Epinephrine, Lidocaine | Canada | Marketed | 2009 |
| XYLOCAINE DENTAL LIDOCAINE HYDROCHLORIDE 2% AND EPINEPHRINE 1:50,0000.02 mg / ml + 20 mg / ml ยท Solution | Epinephrine, Lidocaine | Canada | Marketed | 2010 |
| XYLOCAINE DENTAL WITH EPINEPHRINE0.01MG/ML; 2% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | 0.02MG/ML; 2% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** ยท Injectable | Epinephrine, Lidocaine | United States | Not marketed | 1948 |
| 2% POLOCAINE DENTAL WITH LEVONORDEFRIN 1:20,0000.05 mg / ml + 20 mg / ml ยท Solution | Corbadrine, Mepivacaine | Canada | Cancelled | 1990 |
| 4% ASTRACAINE DENTAL WITH EPINEPHRINE 1:200,000 (0.005MG/ML)40 mg / ml + 0.005 mg / ml ยท Solution | Articaine, Epinephrine | Canada | Cancelled | 1997 |
| 4% ASTRACAINE DENTAL WITH EPINEPHRINE FORTE 1:100,000 (0.01MG/ML)40 mg / ml + 0.01 mg / ml ยท Solution | Articaine, Epinephrine | Canada | Cancelled | 1997 |
| ALL SOLUTIONS ACIDULATED PHOSPHATE FLUORIDE FOAM0.06 % + 2.59 % ยท Solution | Hydrogen fluoride, Fluoride | Canada | Cancelled | 2006 |
| ALVEOLIN | Lidocaine, Hemitartarato epinefrina | Brazil | Cancelled | 2003 |
| BENZOCAINA | Brazil | Cancelled | 2003 |
Where it holds or makes medicines, with how many are current.
| Country | Medicines | Current | Past | Companies |
|---|---|---|---|---|
| Canada | 21 | 8 | 13 | CompaniesAll medicines |
| Brazil | 8 | 0 | 8 | CompaniesAll medicines |
| United States | 6 | 6 | 0 | CompaniesAll medicines |
| Netherlands | 3 | 3 | 0 | CompaniesAll medicines |
| Spain | 1 | 1 | 0 | CompaniesAll medicines |
| Italy | 1 | 1 | 0 | CompaniesAll medicines |
Also in the registers of France, United Kingdom
The ATC groups most of its medicines belong to, largest first.
The active substances in most of its medicines.
How the registers spell it, normalised: legal forms, accents and capitals removed.
Compiled by Prognia from the public medicine and company registers below. Logos are not used.
Companies are grouped by Prognia from the names regulators publish; not an official corporate structure.
Fuente de la informaciรณn: AEMPS (CIMA).
Licence: AEMPS open data reuse with attribution
Source: U.S. FDA, Drugs@FDA / openFDA. FDA does not endorse this site.
Licence: Public domain (U.S. Government work)
Source: BDPM (ANSM, HAS, UNCAM).
Licence: Licence Ouverte v1.0
Anvisa published factual open-data CSV https://dados.anvisa.gov.br/dados/CONSULTAS/PRODUTOS/TA_CONSULTA_MEDICAMENTOS.CSV, HTTP version Mon, 12 Oct 2026 11:45:25 GMT; acquired 12 October 2026; original source states and timestamps retained.
Licence: Brazil federal factual open data, consolidated Decreto 8777/2016 article 4; attribution and third-party exceptions
Health Canada, Drug Product Database, company API, entire response observed 2026-10-10T15:12:05.508784+00:00; native facts projected by Prognia.
Licence: Open Government Licence Canada
Health Canada, Drug Product Database, drugproduct API, entire response observed 2026-10-10T15:12:07.336870+00:00; native facts projected by Prognia.
Licence: Open Government Licence Canada
Fuente de la informaciรณn: Agencia Espaรฑola de Medicamentos y Productos Sanitarios www.aemps.gob.es; CIMA presentaciones, acquired 11 October 2026 UTC; each source response/update date retained.
Licence: AEMPS explicit public open-data reuse for citizens and companies; source attribution and update date required
Fuente de la informaciรณn: Agencia Espaรฑola de Medicamentos y Productos Sanitarios www.aemps.gob.es; CIMA medicamentos, acquired 11 October 2026 UTC; each source response/update date retained.
Licence: AEMPS explicit public open-data reuse for citizens and companies; source attribution and update date required
BDPM / ANSM, HAS and UNCAM; original URLs and each update date retained
Licence: BDPM exact Licence Ouverte v1.0 (October 2011)
Medicines and Healthcare products Regulatory Agency (MHRA), GOV.UK; Category 2 list; publication updated 25 August 2026; acquired 2026-10-15T08:18:48.423930+00:00; original workbook cells and factual authorization/holder projections adapted under Open Government Licence v3.0.
Licence: Open Government Licence v3.0; exact Crown copyright 2026 publication grant
Agenzia Italiana del Farmaco (AIFA); https://drive.aifa.gov.it/farmaci/confezioni_fornitura.csv; HTTP Last-Modified Mon, 12 Oct 2026 23:02:44 GMT; acquired 2026-10-13T17:21:16.224007+00:00; native fields retained, source identifier and role projections are adaptations.
Licence: CC BY 4.0; AIFA published open-data catalog
College ter Beoordeling van Geneesmiddelen, Geneesmiddeleninformatiebank metadata, source update 07-10-2026; downloaded 08-10-2026; factual adaptation.
Licence: Conditional noncreative administrative factual metadata; no dataset-wide CC0 claim
Report an error or request removalCorrections from the company itself are welcome.
Well-known pharmaceutical groups, each with all its companies.