Journal of obesity
Quality of Life in Adults With Severe Obesity: A Systematic Review and Meta-Analysis of Cross-Sectional Studies
By Macedo TSG, Pereira MMDN, Pereira TDAR and 3 others.
Abstract
Purpose
This systematic review aimed to synthesize evidence on the association between severe obesity (body mass index [BMI] ≥ 40 kg/m2) and quality of life (QoL) in adults who had not undergone bariatric surgery or other interventions specifically targeting QoL, and to identify the QoL domains in which lower scores were most consistently observed.
Methods
Cohort and cross-sectional studies published up to March 2024 were eligible. The review protocol was registered in PROSPERO (CRD42023374612). PubMed, Embase, Scopus, Web of Science, SciELO, CINAHL, and LILACS were searched. Two independent reviewers selected studies, extracted data, and assessed methodological quality using the National Heart, Lung, and Blood Institute tool. Findings were synthesized narratively and through an exploratory random-effects meta-analysis of absolute SF-36 mean scores.