Association of regulatory B, T cells and cytokine production with disease stage in non-small cell lung cancer patients: prospective case control study

Background and aim: The role of regulatory B cells (Bregs) cells and regulatory T cells (Tregs) has been little investigated in non-small cell lung cancer (NSCLC). Therefore, we investigated the frequency of circulating Bregs, Tregs cells, and the serum cytokine profile in NSCLC and their association with disease progression.