International journal of nanomedicine
A Protease-Responsive and Protein-Gated Gold Nanocluster Platform for Non-Invasive Urinary Colorimetric Diagnosis of Glioblastoma
By Yang J and Liu X.
Abstract
Background
Glioblastoma multiforme (GBM) diagnosis remains challenging because conventional imaging may have limited ability to distinguish tumor progression or recurrence from treatment-related changes, and robust non-invasive biomarkers are still lacking. This study developed a protease-responsive gold nanocluster platform for urinary colorimetric detection of GBM via a synthetic biomarker strategy.
