Frontiers in oncology
Ginsenoside Rb2 promotes p62-mediated LDHA autophagic degradation to inhibit H3K18la-dependent PD-L1 transcription in cervical cancer
By Wang X, Zhang Z, Chen M and 4 others.
Abstract
Background
Ginsenoside Rb2 has demonstrated antitumor activity in multiple malignancies, yet its role in cervical cancer and the underlying mechanism remain unclear. This study investigated the effects of Rb2 on cervical cancer progression and explored whether metabolic reprogramming contributes to PD-L1 regulation.
