IBRO neuroscience reports
Transient functional preservation precedes retinal ganglion cell degeneration following optic nerve crush
By Yu S, Liu F, Zhao Y and 2 others.
Abstract
Aims
Optic nerve crush (ONC) induces progressive retinal ganglion cell (RGC) degeneration; however, the temporal relationship between functional impairment and structural loss remains incompletely understood. This study investigated early changes in retinal function and subtype-specific RGC responses following ONC to determine whether retinal activity is preserved before substantial RGC degeneration.
