Patient preference and adherence
Medication Adherence Patterns for Patients with Atrial Fibrillation: A Mixed Methods Study to Understand Patient and Clinician Perspectives
By Imboden MT, Gill M, Jones KG and 10 others.
Abstract
Background
Medication adherence is essential for effective atrial fibrillation (AF) management; however, many patients with AF are non-adherent to these medications, necessitating an understanding of adherence barriers. This mixed-methods study aimed to identify factors influencing oral anticoagulant (OAC) adherence.
Methods
A stratified random sample of 2000 patients with non-valvular AF and OAC prescriptions was surveyed from a large, seven state community health system, capturing barriers and facilitators to medication adherence using an adapted version of the Adherence Starts with Knowledge-12 scale. Twenty-eight semi-structured interviews were conducted with a sample of survey respondents to further explore drivers of adherence. Eligible clinicians were surveyed on patient adherence. Survey data were analyzed descriptively and using multivariable regression models. Interview data were analyzed thematically.
