BMC cardiovascular disorders
Albumin-based nutritional-inflammatory indices and prognosis in critically ill patients with acute myocardial infarction: a MIMIC-IV cohort study
By Wang H, Wen X, Huang Y and 1 others.
Abstract
Objective
This study investigated the associations between 12 albumin-based nutritional-inflammatory indices and adverse outcomes in critically ill patients with acute myocardial infarction and compared their prognostic performance.
Methods
A retrospective cohort study was conducted using the MIMIC-IV database, which includes data from 2,255 critically ill AMI patients. Twelve nutritional and inflammatory indices were assessed: Advanced Lung Cancer Inflammation Index (ALI), Blood Urea Nitrogen to Albumin Ratio (BAR), Creatinine to Albumin Ratio (CAR), Controlling Nutritional Status (CONUT) score, Geriatric Nutritional Risk Index (GNRI), Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, Lactate to Albumin Ratio (LAR), Monocyte to Albumin Ratio (MAR), Neutrophil to Albumin Ratio (NAR), Neutrophil Percentage to Albumin Ratio (NPAR), Prognostic Nutritional Index (PNI), and Red Cell Distribution Width to Albumin Ratio (RAR). The primary outcomes were 30-day and 365-day all-cause mortality (ACM), while secondary outcomes included new-onset atrial fibrillation (NOAF), new-onset ventricular arrhythmia (NOVA), and acute heart failure (AHF).
