Early-Onset Radiation-Induced Angiosarcoma of the Breast: A Case Report and Literature Review.

Secondary breast angiosarcomas are rare tumors, and more likely to occur after breast-conserving surgery. They are commonly a late adverse event of radiation therapy that typically presents after ten years of treatment. We report a case of radiation-induced breast angiosarcoma presenting as early as 30 months following the completion of postoperative radiotherapy for breast cancer. Angiosarcoma has a potentially significant risk for local and metastatic recurrence despite total mastectomy. Therefore, a low threshold for suspicion is essential for prompt diagnosis and appropriate treatment.