BMC ophthalmology
Ocular manifestations of lichen planus: a comparative analysis of tear function, choroidal thickness, and retinal parameters
By Çiftci F, An İ, Çelik G and 1 others.
Abstract
Background
To assess tear function, retinal and choroidal thickness, retinal nerve fiber layer (RNFL) thickness, and ganglion cell complex (GCC) thickness in patients with lichen planus (LP) compared with healthy controls with comparable age and sex distribution.
Methods
This prospective case-control study included 35 participants with LP and 35 healthy control participants. Only the right eye of each participant was included in the analysis. Tear function was evaluated using the Schirmer I test and tear break-up time (TBUT). Axial length (AL) was measured using optical biometry, and intraocular pressure (IOP) was measured by pneumotonometry, whereas central retinal thickness (CRT), RNFL thickness, and GCC thickness were assessed using spectral-domain optical coherence tomography (SD-OCT). Choroidal thickness was measured at the subfoveal, nasal 1500 μm, and temporal 1500 μm regions using enhanced depth imaging OCT (EDI-OCT). Intraobserver reliability was evaluated using the intraclass correlation coefficient (ICC).
