medRxiv
Citrulline and Faecal Elastase 1 as a Combined Diagnostic Biomarker for Pancreatic Ductal Adenocarcinoma
By Niazi, U., Roberts, C. A., McDonnell, D. and 6 others.
Abstract
Background
Early detection of pancreatic ductal adenocarcinoma (PDAC) is critical. While faecal elastase-1 (FE-1) is a standard clinical marker for pancreatic function, its diagnostic accuracy for malignancy is limited. We sought to identify plasma metabolites that enhance FE-1 performance in symptomatic "at-risk" patients.
