Association of Insulin Resistance, High-Sensitivity C-Reactive Protein, and Selected Inflammatory Biomarkers with Clinical Phenotypes of Polycystic Ovary Syndrome

Background

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder in which insulin resistance and chronic low-grade inflammation are thought to drive long-term cardiometabolic risk. Whether these abnormalities differ across the four Rotterdam phenotypes remains incompletely defined, particularly in Middle Eastern populations.