Open access journal
Buruli Ulcer Diagnosis: Current Status, Diagnostic Gaps, and Future Prospects for Point-of-care Testing
By Esiere RoseMary Kaiso, Sonrandein Ditimi Bodensibari and Nathaniel Chimeka Deborah.
Abstract
Background
Buruli ulcer (BU), caused by Mycobacterium ulcerans, remains an under-recognised neglected tropical disease whose control is constrained by limited access to accurate, timely diagnosis in the remote, resource-poor settings where it is most prevalent.
Methods
A narrative review of primary diagnostic-accuracy and diagnostic-development literature indexed in PubMed, PLOS Neglected Tropical Diseases, the Journal of Clinical Microbiology, Clinical Infectious Diseases, medRxiv, and World Health Organization (WHO) surveillance publications was conducted to synthesise performance data for established laboratory methods and emerging point-of-care platforms.