ACUMEN INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH
The hygiene hypothesis: How early-life microbial exposure may influence allergic diseases
By Reethika, Kousik, Adhil and 1 others.
Abstract
Over the past half century, allergic diseases such as asthma, atopic eczema, hay fever and food allergy have risen dramatically, particularly in industrialized, urbanized societies. In 1989, epidemiologist David Strachan proposed what became known as the 'hygiene hypothesis': a lack of early-childhood exposure to infectious agents, and more broadly to a diverse microbial environment, may disturb the development of the immune system and predispose a child to allergic disease. Since then, the hypothesis has evolved considerably.
Keywords
- Asthma and respiratory diseases
- hygiene hypothesis
- allergic diseases
- early life microbial exposure
- immune system development
- asthma
- atopic dermatitis
- allergic rhinitis
- food allergy
- industrial society
- infectious agents
- Open access
Source
Published in ACUMEN INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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