Abstract / Summary
The larynx is the area most affected by cancer in the head and neck, with an incidence rate of 100,000/5, and the number of deaths is estimated at 82,000 annually. The research aimed to study the laboratory parameters of the mean platelet volume (MPV), by studying the difference in the mean platelet volume of patients before and after surgery, and then comparing these values with a control group. The research was conducted on all patients who had been diagnosed with laryngeal cancer from the Department of Otorhinolaryngology and Surgery at Tishreen University Hospital in Latakia, and who had undergone surgery for this tumor, after obtaining informed consent. A prospective study was conducted, and the number of patients reached (30) patients. A search form was organized for patients. The research results showed that there were no significant changes in the mean platelet volume (MPV) in Patients With Laryngeal Cancer one week after surgery compared to their values before surgery. Laryngeal cancer patients have significantly higher MPV levels than healthy people, both before and after surgery. The research recommends the importance of conducting further studies to confirm our findings in larger groups of patients. The association of MPV with clinical outcomes for patients should be evaluated and factors that may influence their MPV such as type of cancer and stage of disease should be investigated.