Abstract / Summary
Lacrimal fluid is a complex biological environment that reflects local ocular immunity, neuroinflammation, and systemic metabolism. After the age of 55, the metabolomic diversity of lacrimal fluid decreases dramatically: the number of detectable metabolites drops from 60–440 to a critical threshold of less than 20, which is associated with dry eye syndrome, uveitis, keratitis, glaucoma, diabetic retinopathy, and neurodegenerative diseases. However, standard clinical analyses do not assess the metabolomic diversity of lacrimal fluid. The article shows how the theory of subjectabols allows you to measure the metabolic depletion of lacrimal fluid, what diseases are associated with it, and how foods with a high PC/IT profile, including biogenic nutrition, restore metabolomic diversity. The PC/IT profile is a format for representing two independent indices: the density of objects (PC) and the toxicity index (IT). The entry 175/3 means 175 beneficial molecular species and 3 harmful ones per 100 g of product — this is not a fraction, but two independent numbers side by side, like a blood pressure of 120/80. The profile is tied to the vector of product parameters: variety, origin, method of production, condition, freshness, and storage conditions. A monitoring protocol and practical recommendations for people 55+ are proposed.