Zenodo
Assessment of DNA damage enzyme, oxidative stress, inflammation biomarkers among male scd patients in irrua, edo state, nigeria
By Wisdom Omogbai OHIWEREI and Mathew Folaranmi Olaniyan.
Abstract
Introduction
Sickle cell anemia (SCA) is a severe, hereditary hemoglobinopathy characterized by the mutation of the beta-globin gene, resulting in the production of abnormal hemoglobin S (HbS). Under deoxygenated conditions, HbS polymerizes, causing erythrocytes to adopt a rigid, sickle-like structure.
Aim
This study aimed to assess the roles of oxidative stress, inflammation, DNA damage enzymes, biomarkers among male SCD patients in Irrua, Edo State, Nigeria.
