Abstract / Summary
Abstract ENCe document, produit avec l’assistance de ChatGPT o3 et GPT-5 Thinking, est publié sous la licence Apache 2.0. Il constitue une publication défensive (antériorité) et entre de ce fait dans l’état de la technique au sens des textes applicables : art. 54(2) CBE / CBE (Convention sur le brevet européen), art. L 611-11 CPI (Code de la propriété intellectuelle français), cf. 35 U.S.C. §102(a) (loi américaine sur les brevets), ainsi que les dispositions correspondantes du droit chinois (Loi sur les brevets, art. 22(5)) et japonais (特許法, art. 29(1)). Le rapport décrit une plateforme lichenique extrêmophile modulaire (Cage, Antenne, DRM biologique) pour extraire, confiner et libérer à la demande des complexes organométalliques monoatomiques. Trente-deux innovations sont présentées de manière enabling, chacune classée avec des codes IPC et CPC, et associée à une preuve d’horodatage (RFC 3161 / FreeTSA). Résumé FRThis document, produced with the assistance of ChatGPT o3 and GPT-5 Thinking, is released under the Apache 2.0 licence. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes: EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 CPI (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), together with the corresponding provisions of Chinese Patent Law Art. 22(5) (中华人民共和国专利法) and Japanese Patent Act Art. 29(1) (特許法). The report discloses an extremophile lichen-based, modular bio-foundry platform (“Cage”, “Antenna”, “biological DRM”) to extract, confine and on-demand release monoatomic organometallic complexes. Thirty-two innovations are described in an enabling manner, each assigned IPC and CPC classifications and associated with timestamp proof (RFC 3161 / FreeTSA). Timestamp: 2025-11-26T21:00:00+01:00SHA-256: b98a449d81a75453e5f2bd4a0bc00818a4becb5158446280e37851591561fb4c List of innovations and classifications Ferritin single-atom gold cage — IPC C12N 1/20; CPC C12N 1/205 Encapsulin-directed noble clusters — IPC C12N 1/20; CPC C12N 1/38 In vivo DNA/peptide cages — IPC C12N 15/10; CPC C12N 15/90 MT/PC shuttle to nano-cages — IPC C12N 1/20; CPC C12N 1/38 Controlled acidic bioleaching — IPC C12P 7/00; CPC C12P 7/18 Fluorescence loading sensor — IPC G01N 33/50; CPC G01N 33/569 Auxin phyllotaxis controller — IPC C12N 15/82; CPC C12N 15/90 Spiral mycelial branching network — IPC C12N 1/20; CPC C12N 1/38 Optogenetic spiral growth guidance — IPC C12N 15/82; CPC C12N 15/901 Binary product/destructor vacuoles — IPC C12N 15/82; CPC C12N 15/907 Acoustic vacuolar lock — IPC C12N 15/82; CPC C12N 15/907 Dual acoustic/optical key logic — IPC C12N 15/82; CPC C12N 15/907 Harvest basin bio-reactor — IPC C12M 1/34; CPC C12M 1/34 Tri-partite chimeric chassis — IPC C12N 1/20; CPC C12N 1/38 Symbiotic-dependency containment — IPC C12N 15/82; CPC C12N 15/90 Remediation and co-production process — IPC C22B 3/18; CPC C22B 3/26 Cloud-based bio-foundry control — IPC G06Q 50/02; CPC G06Q 50/26 Functional module-validation kit — IPC G01N 33/50; CPC G01N 33/569 Lyophilised lichen bio-seeds — IPC A01C 1/00; CPC A01C 1/06 Magnetogenetic TRPV-ferritin key — IPC C12N 15/82; CPC C12N 15/907 Artificial hydathodes with guard cells — IPC C12N 15/82; CPC C12N 15/901 Active pulvinus squeezing module — IPC C12N 15/82; CPC C12N 15/907 Multi-metal/alloy-specific cages — IPC C12N 1/20; CPC C12N 1/38 Four-symbiont N-fixing C4 chassis — IPC C12N 1/20; CPC C12N 1/38 Safe ultrasound-key calibration method — IPC G01N 33/50; CPC G01N 33/569 Orbital/space bio-foundry panels — IPC B64G 1/00; CPC B64G 1/24 Secondary valorisation of spent biomass — IPC C12P 19/04; CPC C12P 19/04 Selective P/D DRM membranes — IPC C12N 15/82; CPC C12N 15/907 Extended binary enzyme/substrate system — IPC C12N 15/82; CPC C12N 15/907 Upstream EPS-based metal capture — IPC C12N 1/12; CPC C12N 1/12 Industry 4.0 physical-key management — IPC G06Q 50/02; CPC G06Q 50/26 Standard anti-tamper crash-test protocol — IPC G01N 33/50; CPC G01N 33/569 Keywordsferritin nanocage, gold single-atom, engineered lichen, encapsulin compartment, metal nanocluster, mycobiont chassis, DNA origami cage, peptide polyhedron, metal confinement, metallothionein shuttle, phytochelatin transport, metal uptake, bioleaching module, citric acid secretion, gold solubilisation, fluorescence sensor, gold cluster assay, in vivo QC, auxin circuit, golden angle growth, phyllotaxis control, spiral mycelium, branching control, metal transport network, optogenetic guidance, spiral morphology, light-driven patterning, binary vacuole, biological DRM, product self-destruction, mechanosensitive channel, ultrasound key, controlled exudation, optogenetic lock, dual stimulus, biological authentication, biofoundry reactor, acoustic harvesting, lichen panels, lichen chassis, tri-partite symbiosis, organometallic biofoundry, genetic containment, symbiotic dependency, biosafety design, bioremediation process, monoatomic catalyst, tailings treatment, digital twin, biofoundry control, cloud orchestration, functional assay kit, DRM validation, multi-module test, lyophilised inoculum, field deployment, bioreactor tiles, magnetogenetic key, TRPV-ferritin, EM-triggered release, artificial hydathode, guard cells, clean exudation, active squeezing, pulvinus module, harvest amplification, multi-metal cages, alloy-specific templates, optical fingerprint, nitrogen-fixing partner, C4 photobiont, quadripartite symbiosis, ultrasound key window, safety calibration, QA protocol, space biofoundry, orbital lichen panels, in-situ resource use, usnic acid recovery, spent biomass upcycling, secondary value chain, membrane tuning, ergosterol doping, selective DRM, binary bomb, oxidative enzyme, motif peroxide, EPS capture, photobiont chelation, metal preconcentration, key management, DRM as-a-service, license profiles, anti-tamper assay, crash test, DRM validation protocol