Carboplatin and Etoposide as Effective Fourth-Line Treatment in a patient with Recurrent Oligodendroglioma Complicated by Therapy-Related Acute Myeloid Leukaemia

Objective

A case of recurrent anaplastic oligodendroglioma treated with carboplatin and etoposide as fourth-line chemotherapy is presented. The efficacy of carboplatin and etoposide is highlighted as a salvage regimen and the risk of therapy-related acute myeloid leukaemia (t-AML) as a long-term complication of prolonged alkylating agent exposure.