Public Health of Indonesia
Early Screening Strategies for Thalassemia in Adolescents: A Diagnostic Evaluation in Family-Based Risk Groups
By Natiqotul Fatkhiyah, Apoina Kartini, Sri Achadi Nugraheni and 2 others.
Abstract
Background
Thalassemia remains a major public health burden in Indonesia, particularly among populations with a familial predisposition.
Objective
This study aimed to assess the validity, reliability, sensitivity, and specificity of a thalassemia screening instrument compared with HbA2 examination (hemoglobin electrophoresis) for early detection of thalassemia carriers among adolescents from families with known thalassemia cases.
