Subthreshold Laser as Alternative Treatment for Chronic Central Serous Chorioretinopathy - A Case Series

Purpose

Subthreshold laser is a relatively new and promising therapy for chronic central serous chorioretinopathy (CSCR), particularly in regions where current mainstay therapy in the form of Indocyanine green (ICG)-based photodynamic therapy (PDT) is either too expensive or unavailable. We reported the clinical efficacy of the nondamaging subthreshold laser therapy for chronic CSCR using Endpoint Management™ system. Patients and methods: Eyes with unresolved, chronic CSCR of more than 3 months of duration were treated using PASCAL® (Topcon Medical Laser System) Streamline at 577-nm wavelength, using 200 μm retinal spot sizes. Using Endpoint Management™ Software, the laser power was first titrated with 15-ms pulses and applied over the area of serous retinal detachment and adjacent non-thickened retina using 30% pulse energy with 0.25 spot spacing. Serous retinal detachment was measured between the outer surface of the neurosensory retina and the retinal pigment epithelium (CIRRUS™ HD-OCT, Carl Zeiss Meditec, Inc). Changes in subretinal fluid (SRF) and best corrected visual acuity (BCVA) were measured over 3 months of follow-up as primary outcomes.