Comparative Two-Year Outcomes of Three Different Three-Piece Intraocular Lenses in Flanged Intrascleral Fixation

Background and Objectives: To compare 2-year positional stability, endothelial preservation, and visual outcomes of three three-piece intraocular lenses (IOLs) implanted by the Yamane technique: Eyecryl (polypropylene haptics, 5° haptic angulation), Sensar OptiBlue AR40e (polymethyl methacrylate [PMMA] haptics, 5° haptic angulation), and AcrySof MA60AC (PMMA haptics, 10° haptic angulation). Materials and Methods: Records of 192 consecutive patients (one eye per patient; no bilateral implantation) receiving a study IOL were reviewed; 145 patients (75.5%) completed 24 months of follow-up (Eyecryl 48 eyes, Sensar 48 eyes, MA60AC 49 eyes). Endothelial cell density (ECD) loss and anterior segment OCT measures of decentration, tilt, and anatomical anterior chamber depth (ACD) were modelled with mixed-effects models weighted by stabilised inverse probability of treatment weights, using cluster-robust standard errors.