Life
Pituitary Carcinoma Revisited: A Systematic Review and Individual Patient Data Analysis of Clinicopathological Features, Treatment, and Survival
By Bogdan Florin Iliescu, Loredana Mariana Curecheriu, Bogdan Costăchescu and 2 others.
Abstract
Background
Pituitary carcinoma (PC) is a rare and aggressive pituitary neuroendocrine tumor (PitNET) defined by non-contiguous craniospinal or systemic metastatic spread. Evidence guiding treatment is limited to case reports and case series. This systematic review aimed to characterize the clinicopathological features, treatment patterns, and prognostic determinants of PC through pooled individual patient data (IPD) analysis.
