Diagnostics
Thromboelastographic Assessment of the Differential Sensitivity of Three Contact Activators to Coagulation Factor Deficiencies in Hemocell Environments
By Weiguo Liang, Mao Xia, Junpo Li and 3 others.
Abstract
Background
Thromboelastography (TEG) assesses global coagulation, but its sensitivity for factor deficiencies is reportedly low and may depend on the contact activator. However, the differential TEG sensitivity of contact activators for individual factor deficiencies in whole blood containing platelets and red blood cells remains unclear. This study assessed the relative sensitivity of three contact activators for detecting single coagulation factor deficiencies in reconstituted whole-blood samples using TEG.
