Current Oncology
The Association Between Anastomotic Leak and 5-Year Oncologic Outcomes in Patients Undergoing Colorectal Cancer Resection: A Retrospective Cohort Study
By Ali Farsi and Mohammed Nassif.
Abstract
Background
Anastomotic leak (AL) is a serious complication following colorectal cancer (CRC) resection. Its influence on long-term oncologic outcomes, including recurrence and survival, remains controversial.
Methods
This retrospective cohort study aimed to evaluate the prevalence of AL following CRC resection with anastomosis for stage 1–3 CRC. Clinical, operative, oncologic, and follow-up data were collected. AL was diagnosed within 30 days postoperatively. Primary outcomes included recurrence and mortality.