Cancers
Orlistat Suppresses Small Intestinal Neuroendocrine Tumor Growth Through ATF3-Associated Stress and Ferroptosis-Related Responses—In Vitro and Cell Line Xenograft Evidence
By Xiangrui Zeng, Sixu Chen, Qin Long and 7 others.
Abstract
Background/Objectives: The incidence of small intestinal neuroendocrine tumors (SI-NETs) has increased in recent years, while effective therapeutic options remain limited. This study aimed to investigate the antitumor effects of orlistat on SI-NETs and elucidate the underlying mechanisms.
