Audiology Research
Preoperative Serum Total IgE Category and 6-Month Tympanometric Status After Type I Tympanoplasty for Chronic Otitis Media
By Dan Chen, Yingying You, Luoying Yang and 4 others.
Abstract
Objective
To evaluate whether preoperative serum total IgE, analyzed categorically and continuously, was associated with 6-month postoperative tympanometric status after type I tympanoplasty for chronic otitis media. Tympanic membrane closure and audiometric outcomes were also examined.
Methods
This retrospective study included 171 operated ears from 171 unique patients with chronic otitis media who underwent type I tympanoplasty. The categorical analysis used the institutional assay upper reference limit of 60 IU/mL; a separate analysis treated IgE as a log2-transformed continuous variable. Tympanic membrane closure, tympanometry, and audiometry were assessed at 6 months. Abnormal tympanometric status was defined as a measurable peak pressure < −50 daPa or a type B tympanogram. Multivariable logistic regression evaluated factors associated with abnormal tympanometric status.
