Clinical Characterization of Invasive Meningococcal Disease Epidemic, Uzbekistan, 2026

Tashkent, Uzbekistan, registered 290 invasive meningococcal disease cases during January–April 2026; the case fatality rate was 8.3%. Meningeal signs appeared in only 3.1% of patients and were the sole signs associated with death. Neisseria meningitidis serogroup surveillance and conjugate vaccine introduction will be needed to prevent invasive meningococcal disease in Uzbekistan.