Abstract / Summary
Background and Aims: high-resource Western models restrict adolescent alcohol use disorders (AUD) to static micro-environmental or behavioral variables. This study aims to refute conventional linear predictive frameworks and validate the Global Multidimensional Paradigm against contemporary restrictive models.Design and Setting: A systematic methodology based on the PRISMA statement was employed to contrast transnational linear parameters against structural evidence derived from an epidemiological screening across 21 Latin American countries.Participants and Measurements: a pre-pandemic (2015–2020) screening of 16,921 epidemiological records was conducted, extracting data from 18 included studies to consolidate a total aggregated sample of 5,253 adolescents. Transnational profiles from the World Bank and WHO (cellular toxicity, acute intoxication, and immunosuppression) were analyzed alongside macro-structural variables.
Findings: comparative analysis demonstrates that traditional Anglo-Saxon models fail by omitting global macro-structural forces highlighted by the Lancet Commission. The proposed paradigm reveals that alcohol use disorders are determined by a three-dimensional interaction intersecting the micro-family environment with 21st-century digital dynamics (algorithmic marketing on TikTok and Instagram, e-commerce, and systemic violence), validating Krieger’s eco-social theory of embodiment (2024).
Conclusions: by displacing linear biomedical approaches, this study establishes that adolescent alcohol use disorders constitute the literal biological embodiment of macro-structural inequalities, offering an indispensable new conceptual standard for international epidemiology.
Keywords: adolescence, alcohol use disorders, multidimensional model, biological embodiment, digital networks.