Measurement Science Review
SQUID Magnetometry of Concentration Models of Iron-Containing Proteins
By M. Škrátek.
Abstract
Abstract Concentration models are used to understand the relationship between the concentration of iron-containing proteins and the magnetization of the examined samples when experimentally measuring iron content using SQUID magnetometry. They were prepared for selected proteins: hemoglobin, myoglobin, and ferritin in such a way that their dimensions and concentration resembled the actual samples as closely as possible, and individual proteins were applied as a solution to a diamagnetic matrix. Magnetization measurements with a SQUID magnetometer showed that heme proteins and ferritin have markedly different profiles. The assumption that magnetization increases with increasing concentration, while coercivity remains unchanged, was confirmed. A model of coupling individual contributions of metalloproteins to the resulting magnetization was demonstrated.
Keywords
- Iron Metabolism and Disorders
- Open access
Source
Published in Measurement Science Review. The abstract is shown as published and remains the work of its authors; read the full article at the source.
Prognia lists this article for reference and education. It is not medical advice. Always read the original and follow current guidelines and local protocols before acting on it.
