In vitro Sorption of Lysozyme in Reusable Silicone Hydrogel Contact Lenses: The Impact of Material and Care Solution

Purpose

To characterize lysozyme sorption and denaturation in two SiHy lens materials (comfilcon A and Lotrafilcon B), and compare the effects of three lens care systems – one based on the disinfectant povidone-iodine that contains the protease subtilisin, one based on hydrogen peroxide, and one multipurpose solution – on their ability to remove lysozyme from these lens materials, via established methods.

Methods