Journal of Inflammation Research
Time-Stable Ferroptosis-Related Candidate Genes in Myocardial Ischemia/Reperfusion Injury Identified by Multi-Time-Point Transcriptomic Analysis: Prioritization of NCF2 Through Public Datasets and AC16 Cell Validation
By Rong Huang, Jun Wang, Junchen He and 1 others.
Abstract
Background
Ferroptosis contributes to myocardial ischemia/reperfusion injury (MIRI), but time-stable ferroptosis-related transcriptional features across reperfusion stages and their links to peripheral immune profiles remain unclear. This study aimed to identify time-stable ferroptosis-related candidates in MIRI using public datasets and AC16 hypoxia/reoxygenation experiments.
