Adenomyosis and Endometrial Polyps: A Systematic Review of Coexistence Patterns and Diagnostic Contexts

Purpose

Adenomyosis (AM) and endometrial polyps (EPs) are frequently identified in women evaluated for abnormal uterine bleeding, pelvic pain, infertility, and peri- or postmenopausal symptoms. However, coexistence estimates arise from heterogeneous clinical and diagnostic pathways. We synthesized bidirectional AM–EP coexistence and examined how source population and ascertainment influenced reported prevalence. Patients and Methods: This PROSPERO-registered systematic review (CRD420261304541) followed PRISMA 2020. PubMed, Embase, the Cochrane Library, and Scopus were searched from the earliest date available in each database to July 14, 2026. Studies reporting either direction of AM–EP prevalence were included. Methodological quality was assessed using the Joanna Briggs Institute prevalence checklist. Given clinically heterogeneous populations, denominators, and diagnostic pathways, study-specific estimates were synthesized narratively without pooling.