International Journal of General Medicine
Biliary Microbiology and Antimicrobial Treatment Modification in Patients Undergoing Percutaneous Cholecystostomy for Acute Cholecystitis: A Single-Centre Retrospective Cohort Study
By Berkan Acar, Ali Muhtaroğlu, Selman Alkan and 4 others.
Abstract
Objective
To describe bile culture yield, organism distribution and antimicrobial treatment modification in patients undergoing percutaneous cholecystostomy (PC) for acute cholecystitis who were unsuitable for early cholecystectomy.
Methods
We retrospectively reviewed 84 consecutive patients who underwent PC between December 2021 and December 2025. Index bile cultures were classified as positive, no growth, or not obtained. We analysed organisms, polymicrobial growth, empirical antimicrobial therapy, treatment modification and clinical outcomes by culture status and disease severity.
