Effectiveness of Zinc as an Adjuvant to Standard Therapy Versus Standard Therapy Alone in Children (5-10 Years) with Moderate Persistent Asthma

Abstract Background: Bronchial asthma, a hypersensitivity condition of the airway is increasing significantly in south asia due to rapid modernization and environmental pollution. Limited trial has been conducted on Zinc as adjuvant therapy for Asthma. This randomized controlled trial aimed to evaluate the effectiveness of Zinc in bronchial asthma.

Objective

To determine the effectiveness of zinc as an adjuvant to standard therapy compared to the standard therapy alone in children with moderate persistent asthma. Methodology: This registered randomized controlled trial was done at Department of Pediatric Medicine unit-I, Mayo Hospital, KEMU, Lahore over 6months (1 st April, 2022 to 31st September, 2022) after IRB approval. A total of 84 patients were enrolled and divided randomly by lottery into two groups : Group A( Intervention) who received standard therapy alongwith oral elemental zinc ; Group B(Control) who received only standard therapy. Patients were followed up 4 weekly for 2 months and the results was assessed by Asthma Control Test and Emergency Visit.