Preprints.org
Hydroxypropyl-β-Cyclodextrin-Containing Hypertonic Nasal Spray Versus 0.9% Isotonic Saline in Pollen-Induced Allergic Rhinitis: A Randomised, Double-Blind, Crossover Non-Inferiority Study
By Mösges R, Verfürth HC, Umlauf J and 12 others.
Abstract
Background
/Objectives: Drug-free nasal formulations may provide an alternative or adjunct to pharmacological treatment in patients with allergic rhinitis. This study in-vestigated the clinical performance, tolerability, and safety of a hypertonic nasal spray containing hydroxypropyl-β-cyclodextrin (BDNS) compared with 0.9% isotonic saline in adults with pollen-induced allergic rhinitis.
