Abstract / Summary
Lipedema is a chronic adipose tissue disorder characterized by pain and disproportionate fat distribution. Although exercise is an important component of lipedema management, evidence regarding exercise behavior, physical activity, and related barriers remains limited. This study aimed to investigate exercise behavior, physical activity level, and perceived barriers in women with lipedema compared to healthy controls. In this case-control study, 61 women with lipedema and 58 healthy controls were included. Exercise behavior, physical activity, and perceived barriers were assessed by using the Stages of Exercise Behavior Change Questionnaire, International Physical Activity Questionnaire–Short Form, Self-Perceived Barriers for Physical Activity Questionnaire, respectively. Additionally, lipedema-specific limitations and exercise experiences were recorded through self-reported personal statements. Approximately half of the women with lipedema were in the pre-action stage for exercise behavior, with no significant difference between groups. While total physical activity levels were similar ( p > 0.05), women with lipedema had significantly lower walking activity ( p = 0.028). Perceived barriers related to body image and physical-social anxiety were significantly higher in the lipedema group ( p = 0.014). According to self-reports, the most prominent disease-specific barriers were leg pain (22.95%) and fatigue (21.31%). These findings indicate that, compared to healthy controls, physical activity is not generally reduced in women with lipedema, but walking activity is significantly lower, and body image and physical-social anxiety are perceived as greater barriers to physical activity. Integrating psychological support and symptom-sensitive exercise programming may improve physical activity participation in women with lipedema.