Hypertension
Glycosylated Fibronectin Compared With sFlt-1/PlGF Ratio for Preeclampsia Assessment
By Nouran Elbarbary, Christopher Wang, Ramesh Ganapathy and 6 others.
Abstract
Background
The ratio of sFlt-1 (soluble fms-like tyrosine kinase 1) to PlGF (placental growth factor) is an established biomarker for preeclampsia diagnostic triage. GlyFn (glycosylated fibronectin) measured by point-of-care testing is an alternative rapid assessment from finger-stick blood samples. This study was designed to test the hypothesis that the sensitivity of GlyFn is noninferior to that of the sFlt-1/PlGF ratio in women with suspected preeclampsia.
