Double Versus Single Gloving in Gynecologic and Obstetric Procedures for the Prevention of Surgical Glove Perforation: A Meta-Analysis of Randomized Controlled Trials

Abstract Evidence from other surgical specialties has shown that wearing two pairs of surgical gloves reduces glove perforation and occupational exposure, leading to its widespread adoption in clinical practice. Whether these benefits extend to gynecologic and obstetric procedures remains uncertain. We performed a systematic review and meta-analysis of randomized controlled trials comparing double versus single gloving during gynecologic and obstetric procedures. We searched six electronic databases from their inception to June 3, 2026. The primary outcomes were inner glove perforation, outer glove perforation, and simultaneous perforation of both the inner and outer gloves. Of 252 records identified, 101 underwent title and abstract screening. Six randomized controlled trials were included in the systematic review, and five were eligible for meta-analysis. Compared with single gloving, double gloving significantly reduced the risk of inner glove perforation and simultaneous perforation of both gloves, whereas no significant difference was observed for outer glove perforation. Double gloving also significantly reduced perforations involving the thumb, index finger, and middle finger. Overall, the findings demonstrate that double gloving provides greater protection against glove perforation during gynecologic and obstetric procedures and supports its routine use to improve surgical safety and reduce occupational exposure.