Clinical Case Reports
Suboptimal Response to Eculizumab in Renal‐Limited Thrombotic Microangiopathy Associated With Malignant Hypertension and Monoclonal Gammopathy: A Case Report
By Wenjuan Lei, Tianli Shi, Man Xu and 1 others.
Abstract
ABSTRACT Renal‐limited thrombotic microangiopathy (TMA) is clinically milder but etiologically complex and is often underdiagnosed. This case presents as complement‐mediated TMA with malignant hypertension and monoclonal gammopathy but showed suboptimal response to eculizumab treatment, suggesting heterogeneity in both etiology and treatment outcomes.
Keywords
- complement activation
- eculizumab
- malignant hypertension
- monoclonal gammopathy
- renal failure
- thrombotic microangiopathy
- Open access
Source
Published in Clinical Case Reports. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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