Ethosuximide-induced lupus erythematosus: Unveiling a rare adverse reaction through systematic review

Background

Ethosuximide (ESM) is a first-line anti-seizure medication (ASM) for absence seizures and is generally well-tolerated. However, rare immune-mediated adverse reactions like drug-induced lupus erythematosus (DILE) have been reported. This study aimed to systematically review published reports of ESM-induced lupus erythematosus (LE).