Home Transcranial Direct Current Stimulation With Gamified Cognitive Control Training for Depression: A Randomized Clinical Trial

Importance: Transcranial direct current stimulation (tDCS) has emerged as a home-based treatment in major depressive disorder (MDD), although its effects are typically small to moderate and inconsistently observed. Because tDCS may act synergistically with behavioral interventions, combining both approaches represents a promising strategy for developing more effective home-based treatments for MDD.