Impact of Aerobic Exercise on Endothelial Function and Other Cardiovascular Disease Markers in Health and Disease: A Systematic Review and Meta-analysis with Meta-regression of Randomized Controlled Trials

Background

Aerobic exercise (AE) has long been recognized as a potent stimulus for improving various cardiovascular disease (CVD)-related markers. Although several meta-analyses have focused on some of these markers, no meta-analysis or meta-regression has comprehensively evaluated the influence of multiple CVD-related markers on endothelial function, assessed by brachial-artery flow-mediated dilation (baFMD).