Journal of inflammation research
1H NMR-Based Metabolomics Coupled With Molecular Docking to Explore the Anti-NAFLD Effects of Astragalus Radix and Dioscoreae Rhizoma Herb Pair
Door Miao J, Niu W, Huang B en 2 anderen.
Inhoud in het Engels
Abstract
Introduction
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by lipid accumulation in hepatocytes. Our previous study demonstrated that the herbal pair (HS) of Astragalus Radix (HQ) and Dioscoreae Rhizoma (SY) reduces blood lipids and improves hepatic lipid metabolism in high-fat diet-fed mice.
Purpose
This study aimed to investigate the effects and potential active ingredients of HS in treating NAFLD using 1H NMR urine metabolomics and molecular docking.