Hepatology communications
Sex and racial disparities in clinical outcomes and health resource use among patients with primary biliary cholangitis in the United States
Door Wilder JM, Yang H, Zhang S en 6 anderen.
Inhoud in het Engels
Abstract
Background
Racial and sex disparities have been described in liver conditions, including primary biliary cholangitis (PBC). This study sought to understand how race/ethnicity and sex-based differences impact access to diagnosis, clinical outcomes, health resource use (HRU), and treatment among patients with PBC in the United States (US).
Methods
Komodo Research Database claims data (2016-2023) for adults diagnosed with PBC were analyzed retrospectively. Patients were grouped by race/ethnicity (White, Black, Hispanic, Asian, and Other) and separately by sex (male or female). Clinical characteristics, treatment patterns, and HRU outcomes were assessed pre-index and post-index. The index date was defined as the first claim with a PBC diagnosis code. Statistical significance for comparisons was defined as p<0.05.