Pharmaceuticals
Dose-Related Effects of Cannabidiol on Inflammatory and Redox Responses, Bacterial Dissemination, and Multiorgan Injury in CLP-Induced Septic Rats
Door Ufuk Ülker, Bülent Bayraktar, Tünay Karan en 6 anderen.
Inhoud in het Engels
Abstract
Background
Sepsis couples dysregulated inflammation, oxidative imbalance, microbial dissemination, and multiorgan injury. Cannabidiol (CBD) has anti-inflammatory and redox-modulating properties, but its dose-related effects in polymicrobial sepsis, particularly alongside culture-recoverable bacterial burden, remain incompletely characterized.