Nutrients
Pretreatment Prognostic Nutritional Index Is Associated with Treatment Response and Survival in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma Receiving CAR-T Cell Therapy
Door Zhengyuan Han, Yadi Zhong, Zijian Lv en 2 anderen.
Inhoud in het Engels
Abstract
Background
Clinical outcomes after CAR-T therapy vary substantially in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (r/r B-NHL), and practical markers available before infusion are still limited. The prognostic nutritional index (PNI), calculated from serum albumin and absolute lymphocyte count, reflects both nutritional and immune condition. Whether pretreatment PNI has prognostic value in patients treated with TanCAR7 remains unclear.