Journal of Clinical Medicine
Association Between Post-Cardiopulmonary Bypass Hemodynamics and 30-Day Mortality After Aortic Surgery: A Single-Center, Retrospective Study
Door Changwoo Kim, Woo Jin Kim, Hyun-Seok Kim en 6 anderen.
Inhoud in het Engels
Abstract
Background
We evaluated phase-specific associations between perioperative hemodynamic variables and 30-day mortality following aortic surgery requiring cardiopulmonary bypass (CPB) and to assess the utility of post-CPB variables in risk stratification.
Methods
We analyzed 691 patients who underwent aortic surgery requiring CPB. Hemodynamic variables were assessed during the preoperative, pre-incision, pre-CPB, and post-CPB phases and included heart rate (HR), systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP), shock index (SI; HR/SBP), and modified shock index (MSI; HR/MBP). The primary outcome was 30-day mortality. Holm correction was applied to the between-group comparisons of hemodynamic variables. Adjusted Cox models used ridge penalization and included surgery group, CPB time, and mean post-CPB vasoactive-inotropic score.